Osteoarthritis local integration, illustration 插畫檔

Illustration of the four stages and pathological progression of osteoarthritis. Stage zero depicts a normal articular surface with a smooth and intact cartilage layer. Stage one presents the mild phase, characterised by focal fibrosis and surface roughening. Stage two demonstrates the moderate phase, exhibiting focal fissures or defects within the cartilage layer. Stage three represents the severe phase, showing diffuse full-thickness cartilage loss and severe structural destruction